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Risk-based screening is coming. High-risk clinics need to be ready
The WISDOM trial reported in 2026 that risk-based breast screening was as safe as annual mammograms. What that means for coordination.
The HYPHAE team
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4
min read
The WISDOM trial, reported in 2026, compared risk-based breast screening with annual mammograms and found it as safe. If screening is tailored to each woman’s risk, more women will be identified as high risk, and each will need a different schedule.
That shifts the bottleneck. Estimating risk is becoming easier; keeping every woman on the plan that follows from it is the hard part.
What changes for high-risk clinics
• More women referred, with more varied risk profiles.
• More schedules to run in parallel, often across several sites.
• More need to show, with data, that women stay on their pathway.
HYPHAE works with the risk models and imaging tools centres already use. It records their outputs and turns the centre’s protocol into a schedule for every woman.
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Your protocol, our coordination. See it with your own pathways in a 45-minute demo.
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