HYPHAE
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Her risk journey starts long before diagnosis.
The care pathway coordination platform for breast cancer centres and high-risk clinics, before diagnosis. Every woman, every step, every year, from first risk assessment through menopause.
High-risk breast cancer is a lifelong concern. A woman's care pathway should evolve alongside her.
72%
Lifetime breast cancer risk by age 80 for BRCA1 carriers, against about 12% for women in general.
Kuchenbaecker et al., JAMA 2017
1 in 3
Only 25 to 33% of Czech women who know they carry a variant choose preventive mastectomy. Fear and missing information weigh on that choice.
Masaryk University / CHOICE, 2025
22.8%
Share of at-risk relatives of BRCA carriers who went on to be tested, in an Italian study. Most families never hear the news in a usable form.
Familial Cancer
One pathway, seen from every side of the consultation.
I’m a woman at risk, or family
See my pathway
Your next step, questions for your appointments, and answers you can trust.
Léa, 34 · BRCA1
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I run a high-risk programme
Coordinate my patient
One worklist, your protocol, connected to your hospital systems.
Amélie, nurse coordinator
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I’m a healthcare professional
Train and prepare
Virtual patients, risk-communication tools and protocol-linked resources.
Ida, genetic counsellor
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One care pathway. Every step. For years.
Each woman’s plan is built from her centre’s protocol for her risk route, then kept on track from first assessment through menopause.
A protocol for each kind of high-risk breast cancer.
Inherited · high
BRCA1 and BRCA2
Yearly MRI from 25–30. Risk-reducing surgery discussed with her.
Inherited · high
PALB2
Yearly MRI from 30. Plan guided by her family history.
Inherited · moderate
CHEK2
Yearly mammogram from 40. MRI added with a strong family history.
Inherited · moderate
ATM
Yearly mammogram from 40. MRI considered from 30–35.
Inherited · very high
TP53 (Li-Fraumeni)
Yearly MRI from 20 and whole-body follow-up. No routine mammograms.
Familial
Family history, no variant
Risk estimated with CanRisk. Screening set by her estimated risk.
Treatment-related
Chest radiotherapy before 30
Yearly MRI from 25, or 8 years after treatment.
Biopsy finding
Atypia or LCIS
Yearly mammogram. Risk-reducing medicine often discussed.
HYPHAE runs each risk route on the protocol your clinicians set. Each centre enters its own protocols.
A platform built for the care team.
Made for her.
Eight modules, one pathway at the centre. Every article, word and training case is linked to a step of her pathway.
01
Her personalised pathway
Six steps from risk assessment to menopause, built from your protocol for her risk route, with questions and checklists for each appointment.
For her
02
Coordinator worklist
Every woman, her next step and who is falling behind, in one list with reminders and booking.
Care teams
03
Protocols & EHR integration
Your protocol drives each schedule. FHIR links to the hospital record, imaging and risk models.
Care teams
04
Virtual patient training
Practise disclosing results and discussing surgery, with feedback on every answer.
Professionals
05
Virtual medical library
Guidelines and trusted sources, each with its source, date and reading level.
Everyone
06
Multilingual dictionary
Medical and genetic words in plain language, in five languages, with pronunciation.
Everyone
07
Communication toolkit
Icon arrays, teach-back and question lists to use in the consultation.
Professionals
08
Education & family centre
FAQs, guides, lived experience and a letter to help relatives get tested.
Women & families
Trust and security
Built for the standards that govern health data and medical software in Europe.
HDS
Health data hosting
Hosted with an HDS-certified provider, inside the European Economic Area.
GDPR
GDPR by design
Data minimisation, a legal basis for each use, a data processing agreement with every centre and a named DPO.
ISO 27001
Information security
Run on ISO/IEC 27001 controls, with certification of HYPHAE itself on our roadmap.
CE · MDR
Medical device rules
Coordination stays outside decision support. Any clinical feature is CE marked under the MDR first.
HIPAA
US health privacy
HIPAA safeguards and a business associate agreement before any US patient data is handled.
About HYPHAE
Women at high risk of breast cancer are followed for decades, by services that rarely share one record. We build the engine that keeps them on their pathway because prevention only works if women better understand their care pathway.
“
I chose to focus on the care pathway side of breast cancer after watching a close family member go through a scattered, confusing process, one that added stress and uncertainty to a fight she was already giving everything to win. No one affected by the woes of breast cancer should have to manage the admin of their own care, or sift through endless information online just to understand what comes next.
Massera Ingrid Winigah · CEO & Founder, HYPHAE
Our vision
Every woman at high risk of breast cancer stays on the right plan, for as long as she needs it.
A future where knowing your risk leads to a clear plan, not years of uncertainty, and no woman is lost between appointments, services or generations of her family.
Our mission
Give breast cancer centres, high-risk clinics and their networks one engine to coordinate every woman, every step, every year.
We do it with a shared digital pathway, plain-language knowledge in her own language, tools that help her family make informed choices, and training for the professionals who guide her.
Our approach
One pathway that connects the woman, her family and her care team.
Clinicians set the protocol and make every medical decision. HYPHAE schedules each step, explains it with evidence-based information, and keeps everyone on the same page.
Book a demo
See your high-risk programme running on HYPHAE.
A 45-minute session for breast cancer centres, high-risk clinics, genetics services and regional networks. We walk through the coordinator worklist, your protocols in the engine, her app, and how HYPHAE connects to your hospital record.
We only use these details to answer your request. Please don’t include patient information.
Questions from care teams
What clinicians ask us first.
Does HYPHAE make medical decisions?
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Can we use our own protocols?
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Which women can we follow on HYPHAE?
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How does it connect to our hospital systems?
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Where is health data hosted, and who can see it?
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What does a pilot involve for our team?
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No woman at risk lost to follow-up.
One engine for every step of a high-risk woman’s care pathway, from breast cancer risk to menopause. Fewer women lost, less time spent chasing, one record across services.